Pneumocococcal Immunization

Pneumococcal conjugate vaccine is the second part of our one-two punch against bacterial meningitis (Hib vaccine is the first). Until very recently, pneumococcal vaccine was recommended mostly for adults over 65 years old, and was not licensed at all for children under 2. This is because the type of vaccine that was previously available (pneumococcal polysaccharide vaccine) didn't work very well for young children. Now a different type of vaccine (pneumococcal conjugate vaccine) has been licensed that works for children under 2, and it is finally possible to prevent pneumococcal disease in that vulnerable age group.

Pneumococcal conjugate vaccine is an inactivated (killed) vaccine. It gives immunity against the 7 strains of the pneumococcal bacterium that cause most of the serious infections in children. This vaccine should prevent most meningitis and bacteremia caused by pneumococcal bacteria. However, there are other causes of bacteremia and meningitis, and this vaccine will not prevent them. It will also not prevent all ear infections. Some ear infections are caused by pneumococcal disease, but many are caused by other germs too, and the vaccine will not prevent these.

Children should routinely get 4 doses of the vaccine, one dose each at 2, 4, 6, and 12-15 months of age. Children who begin the series later may not need as many doses. Check with your doctor or clinic for the recommended schedule if your child starts late. Children over 5 years old will generally not get the pneumococcal conjugate vaccine. Older children who need protection from pneumococcal disease (those with certain chronic diseases or damaged immune systems) can get the polysaccharide vaccine, or may get a series that includes both vaccines. Your doctor or clinic staff will tell you if your older children need protection from pneumococcal disease. Pneumococcal vaccine may be given at the same time as other childhood vaccines.

Side Effects from Pneumococcal Immunization

Since the pneumococcal conjugate vaccine is new, the only safety data come from clinical trials. The side effects that have been seen are mainly mild local reactions (redness or tenderness where the shot was given) or a mild fever. The frequency of these reactions vary from study to study, with the highest rates being about 40% of recipients. Moderately serious reactions, such as prolonged crying and febrile seizures (seizures caused by fever) were seen only rarely in these studies, and may not have been caused by the vaccine.

Like any vaccine, or medicine, pneumococcal vaccine could theoretically trigger a serious reaction in someone who is allergic to one of its components. But severe allergic reactions to childhood vaccines are very rare (estimated at around one per million doses), and no child is ever known to have died from an allergic reaction to a vaccine.

Precautions

There are several reasons a doctor might want to delay giving a child a pneumococcal vaccination or not give it at all:

  • A child who has had a life-threatening allergic reaction after a dose of pneumococcal
    vaccine should not get another dose.
  • A child who has a moderate or severe illness on the day a pneumococcal (or any)
    vaccination is scheduled should probably delay the vaccination until he or she has
    recovered.

After Getting Pneumococcal Vaccine . . .

If your child has any serious or unusual problem after getting pneumococcal vaccine, or any other vaccine, call your doctor or take your child to a doctor right away.

U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES
Centers for Disease Control and Prevention
National Center for Immunization and Respiratory Diseases